Peripheral hemophagocytosis in malaria infection

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Peripheral hemophagocytosis in malaria infection.

Examination of the peripheral blood smear showed severe Plasmodium falciparum infection (parasitemia 1% and 1 schizont). In addition, there were numerous examples of hemophagocytosis on the peripheral blood smear. The top left panel shows a monocyte with particulate debris, perhaps remnants of the malarial infection. The top right panel shows a red cell engulfed by a monocyte. On the bottom lef...

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Peripheral blood hemophagocytosis in an unusual lymphoma

We describe a patient with fever, pancytopenia, and hepato-splenomegaly associated with the finding of neoplastic lymphoid cells and histiocytes with hemophagocytosis in the peripheral smear; the diagnostic features were suggestive for a biological overlap between a large B-cell lymphoma with intravascular involvement and the Asian variant of intravascular B-cell lymphoma.

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Potent in vivo anti-malaria activity of Goniothalamin against rodent malaria parasite infection in mice

Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...

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Potent in vivo anti-malaria activity of Goniothalamin against rodent malaria parasite infection in mice

Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...

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Laboratory diagnosis methods of malaria infection

Background and Aim: To manage and control malaria - one of the most important infectious diseases in tropical and subtropical regions – a quick and accurate malaria diagnosis method is necessary as a high priority. For this purpose, several methods have been developed for the diagnosis of malaria, and currently, the examining the peripheral blood slide with an optical microscope as a gold stand...

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ژورنال

عنوان ژورنال: Blood

سال: 2012

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood-2011-02-336420